The Suitability of Some Copper Preparations for Parenteral Copper Therapy in Sheep
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چکیده
The storage of copper by adult Merino sheep of normal copper status has been measured in liver biopsy samples drawn at weekly intervals following subcutaneous and intramuscular injections of copper glycine cerate (90 mg Cu) and aqueous suspensions of copper calcium ethylenediaminetetra-acetic acid (EDTA) and copper methionine complexes (each 100 mg Cu) . The glycine and EDTA preparations safely and effectively induced maximum copper storage within three weeks and one week respectively, with relatively mild local reactions to the subcutaneous injections and no visible or palpable reactions to the intramuscular injections. The copper storage following copper methionine administration was highly variable, and a cold abscess developed at each injection site. The EDTA suspension appeared suitable for mass inoculation.
منابع مشابه
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